Characterization of a 1-bp Deletion in the gE-Crystallin Gene Leading to a Nuclear and Zonular Cataract in the Mouse
نویسندگان
چکیده
PURPOSE. A previous study had found a mouse mutant to have bilateral nuclear cataract with zonular opacity after paternal irradiation with g-rays. The mutation was then demonstrated to be allelic with the Cat2 group of dominant cataract mutations and was referred to as Cat2 in a later study. Because several members of this group have been confirmed as mutations in the gene cluster coding for g-crystallins (Cryg), these genes were now tested as candidates for Cat2.
منابع مشابه
A 6-bp deletion in the Crygc gene leading to a nuclear and radial cataract in the mouse.
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